Anti-ACVRL1 antibody(2A1), IgG1 Chimeric mAb
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| Amount : | 10 μg |
| Isotype : | Rabbit/Human Fc chimeric IgG1 |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % � 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20�C to -80�C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80�C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Gene : | ACVRL1 |
| Uniprot ID : | P37023 |
| Alternative Name : | ACVRLK1;ALK-1;ALK1;HHT;HHT2;ORW2;SKR3;TSR-I |
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
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For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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