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  7. Anti-Adiponectin (Marker of Obesity) Monoclonal Antibody(Clone: ADPN/1370)

Anti-Adiponectin (Marker of Obesity) Monoclonal Antibody(Clone: ADPN/1370)

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Fig. 1: Formalin-fixed, paraffin-embedded human Kidney stained with Adiponectin Mouse Monoclonal Antibody (ADPN/1370).

Anti-Adiponectin (Marker of Obesity) Monoclonal Antibody(Clone: ADPN/1370)
Anti-Adiponectin (Marker of Obesity) Monoclonal Antibody(Clone: ADPN/1370)
Anti-Adiponectin (Marker of Obesity) Monoclonal Antibody(Clone: ADPN/1370)
Anti-Adiponectin (Marker of Obesity) Monoclonal Antibody(Clone: ADPN/1370)

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Fig. 1: Formalin-fixed, paraffin-embedded human Kidney stained with Adiponectin Mouse Monoclonal Antibody (ADPN/1370).
Fig. 2: Western blot Analysis of human Kidney lysate using Adiponectin Mouse Monoclonal Antibody (ADPN/1370).
Fig. 3: SDS-PAGE Analysis Purified Adiponectin Mouse Monoclonal Antibody (ADPN/1370). Confirmation of Integrity and Purity of Antibody.
Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using Adiponectin Mouse Monoclonal Antibody (ADPN/1370). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3554

Clone name : ADPN/1370
Clonality : Monoclonal
Application : WB, IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG2b, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : ADIPOQ
Gene ID : 9370
Uniprot ID : Q15848
Alternative Name : Adiponectin; Adipocyte complement-related 30kDa protein (ACRP30); Adipocyte-specific secretory protein; Adiponectin, C1Q and collagen domain containing (ACDC); ADIPOQ; Adipose most abundant gene transcript 1 protein; Adipose specific collagen like factor; ADIPQTL1; ADPN; APM-1; Gelatin-binding protein 28 (GBP28)
Immunogen Information : Recombinant human Adiponectin protein fragment (around aa 145-226) (exact sequence is proprietary)
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight throµgh direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.

Western Blot (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-Adiponectin (Marker of Obesity) Monoclonal Antibody(Clone: ADPN/1370)

Product code: 36-3554
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