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  7. 36-3419

Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2667)

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Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2667)

Fig. 1: SDS-PAGE Analysis Purified BAP1 Mouse Monoclonal Antibody (BAP1/2667). Confirmation of Purity and Integrity of Antibody.

Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2667)
Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2667)

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Fig. 1: SDS-PAGE Analysis Purified BAP1 Mouse Monoclonal Antibody (BAP1/2667). Confirmation of Purity and Integrity of Antibody.
   
Fig. 1: SDS-PAGE Analysis Purified BAP1 Mouse Monoclonal Antibody (BAP1/2667). Confirmation of Purity and Integrity of Antibody.
Fig. 2: Analysis of Protein Array containing more than 19,000 full-length human proteins using BAP1 Mouse Monoclonal Antibody (BAP1/2667). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3419

Clone name : BAP1/2667
Application : ELISA
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $429.00 

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  • Antigen Details
  • Description
  • Product Info
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Gene : BAP1
Gene ID : 8314
Uniprot ID : Q92560
Alternative Name : BAP1; BRCA1 associated protein 1; Cerebral protein 13; Cerebral protein 6; HUCEP 13; Hucep 6; HUCEP13; Hucep6; TPDS; Ubiquitin carboxy terminal hydrolase; Ubiquitin carboxyl terminal hydrolase BAP1; UCHL2
Amount : 100 µg
Isotype : Mouse IgG2b, kappa
Immunogen Information : Recombinant human BAP1 protein fragment (around aa 191-326) (exact sequence is proprietary)
The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

ELISA (For coating, order Ab without BSA); Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-BAP1 (BRCA1 Associated Protein 1) Monoclonal Antibody(Clone: BAP1/2667)

Product code: 36-3419
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