Anti-BMI1 (Oncogene and Stem Cell Marker) Monoclonal Antibody(Clone: BMI1/2689)

Name: Anti-BMI1 (Oncogene and Stem Cell Marker) Monoclonal Antibody(Clone: BMI1/2689)
Brand: Abeomics
SKU: 36-3150
Price: 429.0000 USD
Availability: InStock
Rating: 5 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with BMI1-Monospecific Mouse Monoclonal Antibody (BMI1/2689).

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Fig. 1: Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with BMI1-Monospecific Mouse Monoclonal Antibody (BMI1/2689).

Fig. 2: Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with BMI1-Monospecific Mouse Monoclonal Antibody (BMI1/2689).

Fig. 3: Western Blot Analysis of Human 293T cell lysate using BMI1-Monospecific Mouse Monoclonal Antibody (BMI1/2689).

Fig. 4: SDS-PAGE Analysis of Purified BMI1-Monospecific Mouse Monoclonal Antibody (BMI1/2689). Confirmation of Purity and Integrity of Antibody.

Fig. 5: Analysis of Protein Array containing more than 19,000 full-length human proteins using BMI1-Monospecific Mouse Monoclonal Antibody (BMI1/2689) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3150

Clone name :	BMI1/2689
Application :	WB, IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS


Gene :	BMI1
Gene ID :	648
Uniprot ID :	P35226
Alternative Name :	B lymphoma Mo MLV insertion region 1 homolog; BMI1; BMI1 polycomb ring finger oncogene; FLVI2/BMI1; Oncogene BMI1; PCGF4; Polycomb complex protein BMI-1; Polycomb group ring finger 4; RING finger protein 51; RNF51
Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Immunogen Information :	Recombinant fragment of human BMI1 protein (around aa 142-326) (exact sequence is proprietary)

The B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1) is a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies.

Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Western Blot (1-2µg/ml);Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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