Anti-BRCA1 (Breast Marker) Monoclonal Antibody(Clone: BRCA1/2986)
Fig. 1: Analysis of Protein Array containing more than 19,000 full-length human proteins using BRCA-1 Mouse Monoclonal Antibody (BRCA1/2986) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
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Product code: 36-3211
|Clone name :||BRCA1/2986|
|Gene ID :||672|
|Uniprot ID :||P38398|
|Alternative Name :||BRCA1; Breast and ovarian cancer susceptibility protein 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; PSCP; RING finger protein 53; RNF53|
|Amount :||100 µg|
|Isotype :||Mouse IgG1, kappa|
|Immunogen Information :||Recombinant fragment (around aa 445-620) of human BRCA1 protein (exact sequence is proprietary)|
|Content :||200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.|
|Storage condition :||Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.|
ELISA (For coating use Ab at 2-4µg/ml, order Ab without BSA), Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.