PE Conjugated, Anti-CD102 / ICAM-2 Monoclonal Antibody (Clone:CBR-IC2/2)
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Amount : | 100 tests |
Isotype : | Mouse IgG2a |
Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.
Subcellular location: | Membrane, Cell projection |
BioGrid: | 109611. 18 interactions. |
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