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  7. Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)

Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)

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Fig. 1: Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with CD137L-Monospecific Mouse Monoclonal Antibody (CD137L/1547).

Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)
Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)
Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)
Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)

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Fig. 1: Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with CD137L-Monospecific Mouse Monoclonal Antibody (CD137L/1547).
Fig. 2: Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with CD137L-Monospecific Mouse Monoclonal Antibody (CD137L/1547).
Fig. 3: SDS-PAGE Analysis Purified CD137L-Monospecific Mouse Monoclonal Antibody (CD137L/1547). Confirmation of Purity and Integrity of Antibody.
Fig. 4: Flow Cytometric Analysis of PFA-fixed HEK293 cells using CD137L-Monospecific Mouse Monoclonal Antibody (CD137L/1547) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).

Product code: 36-3431

Clone name : CD137L/1547
Clonality : Monoclonal
Application : FACS, IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG2a, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : TNFSF9
Gene ID : 8744
Uniprot ID : P41273
Alternative Name : 4-1BB ligand; 4-1BBL; CD137L; ILA ligand (TNF related); Ly63l; Tumor necrosis factor ligand 5A (TNLG5A); Tumor necrosis factor ligand superfamily member 9 (TNFSF9)
Immunogen Information : Recombinant full-length human CD137L protein
TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thoµght to be involved in T cell-tumor cell interaction.

Flow Cytometry (1-2µg/million cells in 0.1ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-CD137L / 4-1BBL / TNFSF9 Monoclonal Antibody(Clone: CD137L/1547)

Product code: 36-3431
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