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    7. Anti-CD14 / LPS-receptor Monoclonal Antibody (Clone:MEM-18)

    Anti-CD14 / LPS-receptor Monoclonal Antibody (Clone:MEM-18)

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    Anti-CD14 / LPS-receptor Monoclonal Antibody (Clone:MEM-18)

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    Product code: 30-1118

    Clone name : MEM-18
    Clonality : Monoclonal
    Application : FACS
    Reactivity : Non-Human Primates

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    0.1 mg
    $339.00  $271.20 

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    • Antigen Details
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    Format : Purified
    Amount : 0.1 mg
    Isotype : Mouse IgG1
    Purification : Purified by protein-A affinity chromatography
    Storage condition : Store at 2-8°C. Do not freeze.
    Gene : CD14
    Gene ID : 929
    Uniprot ID : P08571
    Alternative Name : CD14
    Immunogen Information : A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.

    The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked extracellular membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.

    The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked extracellular membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.

    Flow Cytometry Recommended dilution:4 µg/ml
    Immunoprecipitation Western Blotting ELISA The antibody MEM-18 has been tested as the detection antibody in a sandwich ELISA for analysis of human CD14 in combination with antibody B-A8 . Functional Application The antibody MEM-18 completely blocks binding of fluorescein (FITC) - labeled bacterial LPS to the monocyte surface and it also blocks the binding of CD14 to the extracellular TLR2 domain.

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Cell membrane, Secreted, Membrane raft, Golgi apparatus
    Post transnational modification: N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
    Tissue Specificity: Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
    BioGrid: 107367. 35 interactions.
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    Anti-CD14 / LPS-receptor Monoclonal Antibody (Clone:MEM-18)

    Product code: 30-1118
    *specify in mg or ml

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