Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Other Kits
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Apoptosis
  6. /
  7. Mouse Monoclonal Antibody to p53 (Clone : 2G5F7)(Discontinued)

Mouse Monoclonal Antibody to p53 (Clone : 2G5F7)(Discontinued)

Share:

Figure-1 : Flow cytometric analysis of p53 Antibody (Clone: 2G5F7) on HEK293 cells at 2 µg for 1 x 10^6 cells. Red histogram represents p53 Antibody (Clone: 2G5F7) and green histogram represents isotype control.

Mouse Monoclonal Antibody to p53 (Clone : 2G5F7)(Discontinued)
Mouse Monoclonal Antibody to p53 (Clone : 2G5F7)(Discontinued)

Roll over image to zoom in

   
Figure-1 : Flow cytometric analysis of p53 Antibody (Clone: 2G5F7) on HEK293 cells at 2 µg for 1 x 10^6 cells. Red histogram represents p53 Antibody (Clone: 2G5F7) and green histogram represents isotype control.
Figure-2 : Western blot analysis of p53 Antibody (Clone: 2G5F7) at 1 µg/ml on UV-treated HEK 293 cell lysates, IRDye 800 Conjugated Goat Anti-Mouse IgG was used as secondary Antibody.

Product code: 45-1065

Clone name : 2G5F7
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Format : Purified
Amount : 40 µg
Isotype : Mouse IgG2b
Purification : Protein A chromatography
Content : 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Storage condition : The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Gene : TP53
Gene ID : 7157
Uniprot ID : P04637
Alternative Name : Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
Immunogen Information : Human recombinant wild type p53

The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. It is situated at the crossroads of signalling pathways that are essential for cell growth regulation and apoptosis. In normal unstressed cells, the level of p53 protein is downregulated via the binding of proteins such as MDM2, COP1, PIRH2 or JNK that promote p53 degradation via the ubiquitin/proteasome pathway. As most of these genes are up regulated by p53, this lead to a regulation loop that will keep p53 level very low in a normal cells. Alternative splicing of the human p53 gene gives rise of p53 beta, p53 gamma, Delta 40p53 (also known as p44, p47 or delat N p53), Delta 40p53 beta, Delta 40 p53 gamma, Delta 133p53, Delta 133p53 beta, and Delta 133p53 gamma. p53 Antibody (2G5F7), mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human recombinant wild type p53 (wt p53).

ELISA: 0.05-0.1 µg/ml
Western blot: 1-2 µg/ml
Flow cytometry: 2 µg for 1 x 106 cells

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: Sumoylated with SUMO1. Sumoylated at Lys-386 by UBC9.
Tissue Specificity: Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner. Isoform 2 is expressed in most normal tissues but is not detected in brain, lung, prostate, muscle, fetal brain, spinal cord and fetal liver. Isoform 3 is expressed in most normal tissues but is not detected in lung, spleen, testis, fetal brain, spinal cord and fetal liver. Isoform 7 is expressed in most normal tissues but is not detected in prostate, uterus, skeletal muscle and breast. Isoform 8 is detected only in colon, bone marrow, testis, fetal brain and intestine. Isoform 9 is expressed in most normal tissues but is not detected in brain, heart, lung, fetal liver, salivary gland, breast or intestine.
BioGrid: 113010. 1093 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Monoclonal Antibody to CD45 / LCA (Leucocyte Marker)(Clone : SPM496)

Monoclonal Antibody to CD45 / ...

details-Monoclonal Antibody to CD45 / LCA (Leucocyte Marker)(Clone : SPM496)
Anti-Human IL-6 (Sarilumab) – Fc Muted™ Biotin

Anti-Human IL-6 (Sarilumab) –...

details-Anti-Human IL-6 (Sarilumab) – Fc Muted™ Biotin
Anti-Human TNF alpha (Adalimumab) – PE

Anti-Human TNF alpha (Adalimum...

details-Anti-Human TNF alpha (Adalimumab) – PE
Anti-Cytokeratin 18 Monoclonal Antibody (Clone:DC-10)

Anti-Cytokeratin 18 Monoclonal...

details-Anti-Cytokeratin 18 Monoclonal Antibody (Clone:DC-10)
Anti-SOX-10 Monoclonal Antibody (Clone:IHC010)-Ready to Use

Anti-SOX-10 Monoclonal Antibod...

details-Anti-SOX-10 Monoclonal Antibody (Clone:IHC010)-Ready to Use
SARS-CoV-2 Inhibitor Screening Kit

SARS-CoV-2 Inhibitor Screening...

details-SARS-CoV-2 Inhibitor Screening Kit
Recombinant Human Leukocyte Cell-Derived Chemotaxin 2

Recombinant Human Leukocyte Ce...

details-Recombinant Human Leukocyte Cell-Derived Chemotaxin 2

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin

Related Products

Polyclonal antibody to NALP4 (PAN-2)

Polyclonal antibody to NALP4 (PAN-2)

Polyclonal antibody to Livin (KIAP)

Polyclonal antibody to Livin (KIAP)

Mouse Monoclonal Antibody to PTP1B (Clone: 107AT690)(Discontinued)

Mouse Monoclonal Antibody to PTP1B (Clone: 107AT690)(Discontinued)

New Products

Recombinant TLR2 Protein with human Fc Tag

Recombinant TLR2 Protein with human Fc Tag

Recombinant human TLR3 protein with C-terminal mouse Fc tag

Recombinant human TLR3 protein with C-terminal mouse Fc tag

Anti-IL-17A (Taltz) (Ixekizumab biosimilar) mAb

Anti-IL-17A (Taltz) (Ixekizumab biosimilar) mAb

close

Please Login to write a Review !!


close

Mouse Monoclonal Antibody to p53 (Clone : 2G5F7)(Discontinued)

Product code: 45-1065
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart