Anti-CD160 Monoclonal Antibody (Clone:BY55)-APC Conjugated
Shipping Info:
For estimated delivery dates, please contact us at support@abeomics.com
Amount : | 100 tests |
Isotype : | Mouse IgM |
Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.
Subcellular location: | Cell membrane |
Tissue Specificity: | Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes. |
BioGrid: | 116299. 41 interactions. |
There are currently no product reviews
|