Anti-CD163 Monoclonal Antibody (Clone:GHI/61) Biotin Conjugated

Product code: 30-1453BT

Clone name : GHI/61
Clonality : Monoclonal
Application : IP, FACS, WB
Reactivity : Human
Conjugate : Biotin

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0.1 mg

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Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD163
Gene ID : 9332
Uniprot ID : Q86VB7
Alternative Name : CD163, M130
Immunogen Information : Hairy cell leukemia cells

CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.

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