Anti-CD27 antibody(DM58), Rabbit mAb
|Amount :||100 µg|
|Isotype :||Rabbit IgG|
|Purification :||Purified from cell culture supernatant by affinity chromatography|
|Content :||Preservative: 0.1% Procline 300
Constituents: 50% Glycerol; PBS,pH 7.4; 0.1% BSA
|Storage condition :||Store at -20°C for 12 months (Avoid repeated freezing and thawing)|
|Alternative Name :||CD27, TNFRSF7, S152, T14, Tp55|
|Immunogen Information :||Recombinant human CD27 (Ala20-Arg191) produced by using human HEK293 cells|
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Recommended Dilutions ELISA 1/5000-10000;FACS 1/100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.