Anti-CD28 Monoclonal Antibody(Clone: CB28)-CF488
Fig. 1: SDS-PAGE Analysis Purified CD28 Mouse Monoclonal Antibody (CB28). Confirmation of Integrity and Purity of Antibody.
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| Amount : | 0.5 ml at 100µg/ml |
| Isotype : | Mouse IgG1, kappa |
| Content : | Antibody Purified from Bioreactor Concentrate by Protein A/G and conjµgated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format. |
| Storage condition : | Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. |
Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Flow Cytometry: 5ul per test per one million cells (or 5ul per 100ul of whole blood)Immunofluorescence (1:50-1:100)Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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