Anti-CD38 antibody(DM28), Rabbit mAb
|Amount :||100 µg|
|Isotype :||Rabbit IgG|
|Purification :||Purified from cell culture supernatant by affinity chromatography|
|Storage condition :||Store at -20°C for 12 months (Avoid repeated freezing and thawing)|
|Alternative Name :||T10, cADPr hydrolase 1|
|Immunogen Information :||Recombinant human CD38 (Val43-IIe300) produced by using human HEK293 cells|
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Recommended Dilutions ELISA 1/5000-10000; FACS 1/100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.