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  7. Anti-CD40, Mouse Monoclonal Antibody(Clone: FGK45.5)

Anti-CD40, Mouse Monoclonal Antibody(Clone: FGK45.5)

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Anti-CD40, Mouse Monoclonal Antibody(Clone: FGK45.5)

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Product code: 36-3821

Clone name : FGK45.5
Clonality : Monoclonal
Application : FACS, IF
Reactivity : Mouse

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Rat IgG2a, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene ID : 21939
Uniprot ID : P27512
Alternative Name : B cell surface antigen CD40, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TRAP, IMD3, IGM, Tnfrsf5, HIGM1, GP39, T-BAM
Immunogen Information : Purified recombinant Mouse CD40 fusion protein
Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.

Functional Studies (Order Antibody without BSA & Azide); Flow Cytometry (0.5-1µg/million cells in 0.1ml); Immunofluorescence (0.5-1µg/ml)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-CD40, Mouse Monoclonal Antibody(Clone: FGK45.5)

Product code: 36-3821
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