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    7. Anti-CD81 Monoclonal Antibody (Clone:M38)-Low Endotoxin

    Anti-CD81 Monoclonal Antibody (Clone:M38)-Low Endotoxin

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    Figure-1: Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD81 (M38) purified antibody (low endotoxin, concentration in sample 4 μg/ml) GAM APC.

    Anti-CD81 Monoclonal Antibody (Clone:M38)-Low Endotoxin
    Anti-CD81 Monoclonal Antibody (Clone:M38)-Low Endotoxin
    Anti-CD81 Monoclonal Antibody (Clone:M38)-Low Endotoxin

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    Figure-1: Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD81 (M38) purified antibody (low endotoxin, concentration in sample 4 μg/ml) GAM APC.
    Figure-2: Western blotting analysis of human CD81 using mouse monoclonal antibody M38 on lysate of Jurkat cell line under non-reducing conditions. Nitrocellulose membrane was probed with 2 µg/ml of mouse anti-human CD81 monoclonal antibody M38 followed by IRDye800-conjugated anti-mouse secondary antibody. A specific band was detected for CD81 at approximately 25 kDa.
    Figure-3: Separation of human lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD81 (M38) purified antibody (low endotoxin, concentration in sample 4 μg/ml) GAM APC.

    Product code: 30-1618

    Clone name : M38
    Clonality : Monoclonal
    Application : FACS
    Reactivity : Human

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    0.1 mg
    $356.00  $284.80 

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    • Product Info
    • Antigen Details
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    Format : Low Endotoxin
    Amount : 0.1 mg
    Isotype : Mouse IgG1
    Purification : Purified by protein-A affinity chromatography
    Storage condition : Store at 2-8°C. Do not freeze.
    Gene : CD81
    Gene ID : 975
    Uniprot ID : P60033
    Alternative Name : CD81, TAPA1, TSPAN28
    Immunogen Information : MOLT-4 (human T-ALL cell line)

    CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

    Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
    Flow cytometry: recommended dilution: 1 μg/ml.
    Western blotting: recommended dilution: 1-2 μg/ml; positive control: Jurkat cells, non-reducing conditions.

     

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Basolateral cell membrane
    Post transnational modification: Not glycosylated.
    Tissue Specificity: Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
    BioGrid: 107413. 201 interactions.
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    Anti-CD81 Monoclonal Antibody (Clone:M38)-Low Endotoxin

    Product code: 30-1618
    *specify in mg or ml

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