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  7. Anti-CD81 / TAPA-1 Monoclonal Antibody(Clone: 1.3.3.22)

Anti-CD81 / TAPA-1 Monoclonal Antibody(Clone: 1.3.3.22)

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Fig. 1: Formalin-fixed, paraffin-embedded human Lymph Node stained with CD81 Mouse Monoclonal Antibody (1.3.3.22).

Anti-CD81 / TAPA-1 Monoclonal Antibody(Clone: 1.3.3.22)
Anti-CD81 / TAPA-1 Monoclonal Antibody(Clone: 1.3.3.22)

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Fig. 1: Formalin-fixed, paraffin-embedded human Lymph Node stained with CD81 Mouse Monoclonal Antibody (1.3.3.22).
Fig. 2: Formalin-fixed, paraffin-embedded human Tonsil stained with CD81 Mouse Monoclonal Antibody (1.3.3.22).

Product code: 36-3666

Clone name : 1.3.3.22
Clonality : Monoclonal
Application : FACS, IF, WB, IHC
Reactivity : Human, Mouse, Rat

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG1, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : CD81
Gene ID : 975
Uniprot ID : P60033
Alternative Name : CD81; Target of the antiproliferative antibody 1 (TAPA-1); Tetraspanin-28; Tspan-28
Immunogen Information : B-Cell line derived from a Burkitt lymphoma
Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Functional Studies (Order Ab without Azide);Flow Cytometry (0.5-1µg/million cells); Immunofluorescence (0.5-1µg/ml); Western Blot (0.5-1.0µg/ml for 2 hours at RT);Immunohistochemistry (Formalin-fixed) (2-4µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-CD81 / TAPA-1 Monoclonal Antibody(Clone: 1.3.3.22)

Product code: 36-3666
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