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  7. Anti-Cytokeratin 19 Monoclonal Antibody (Clone:IHC019)

Anti-Cytokeratin 19 Monoclonal Antibody (Clone:IHC019)

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Figure 1: Immunohistochemical analysis of Cytokeratin 19 (Clone: IHC019) on Colon

Anti-Cytokeratin 19 Monoclonal Antibody (Clone:IHC019)

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Product code: 44-1029

Clone name : IHC019
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •  0.5 ml

  • $269.00 

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse lgG1
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : KRT19
Gene ID : 3880
Uniprot ID : P08727
Alternative Name : KRT19
Immunogen Information : Recombinant Human Cytokeratin 19

Cytokeratin 19 (CK19) forms intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue and provides mechanical support. Anti-Cytokeratin 19 stains epithelia and epithelial malignancies such as carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Cytokeratin 19 is a useful marker for distinguishing hepatocellular carcinoma from intrahepatic cholangiocarcinoma. This differentiation is improved when stained in combination with Cytokeratin 7, CAM5.2l, Ber-EP4/MOC31, HepPar1 and TTF1. Cytokeratin 19 staining can also be used to recognize thyroid papillary carcinomas.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Tissue Specificity: Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
BioGrid: 110078. 63 interactions.
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Anti-Cytokeratin 19 Monoclonal Antibody (Clone:IHC019)

Product code: 44-1029
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