Anti-Frataxin (Mitochondrial Marker) Monoclonal Antibody(Clone: rFXN/2124)
Fig. 1: SDS-PAGE Analysis Purified Frataxin Recombinant Mouse Monoclonal Antibody (rFXN/2124). Confirmation of Purity and Integrity of Antibody.
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| Amount : | 100 µg |
| Isotype : | Mouse IgG1, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | FXN |
| Gene ID : | 2395 |
| Uniprot ID : | Q16595 |
| Alternative Name : | CyaY; d-FXN; FARR; Frataxin mature form; Frataxin (81-210); FRDA; Friedreich ataxia protein; Fxn; i-FXN; m56-FXN; m78-FXN; m81-FXN; X25 |
| Immunogen Information : | Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary) |
Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix sµggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA);
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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