Anti-HLA-Class I Monoclonal Antibody (Clone:W6/32)
|Amount :||0.1 mg|
|Isotype :||Mouse IgG2a|
|Purification :||Purified by protein-A affinity chromatography|
|Storage condition :||Store at 2-8°C. Do not freeze.|
|Uniprot ID :||P01892|
|Alternative Name :||HLA-A, HLAA|
|Immunogen Information :||Membrane of human tonsil cells|
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
Flow Cytometry Immunoprecipitation Western Blotting Application note: Non-reducing conditions. Immunohistochemistry (frozen sections) Immunocytochemistry ELISA Mass Cytometry Functional Application The antibody W6/32 is suitable as a positive control for HLA tissue typing.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Subcellular location:||Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus, Endosome membrane, Lysosome membrane|
|BioGrid:||109360. 40 interactions.|