Anti-Hu PODXL Purified PE Conjugated
Figure 1: Separation of HeLa cells stained using anti-human PODXL (PcMab-47) PE antibody (red-filled) from HeLa cells stained using mouse IgG1 isotype control (MOPC-21) PE antibody (black-dashed) in flow cytometry analysis (surface staining).
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| Format : | Purified |
| Amount : | 0.1 mg |
| Purification : | Purified by protein-A affinity chromatography. |
| Content : | Concentration:0. 1 mg/ml,Storage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
PODXL is a highly glycosylated sialomucin, which is expressed in many types of tumors, as well as it is a well known marker of embryonic stem cells. Overexpression of PODXL is an independent predictor of cancer progression, metastasis, and poor outcome. PODXL promotes tumor growts and invasiveness, and is a potential target for antibody therapy.
Specificity :The mouse monoclonal antibody PcMab-47 recognizes a glycosylation-dependent epitope (aa 207-210) on human PODXL, a highly glycosylated transmembrane glycoprotein expressed above all in many types of cancer tissues, and on embryonic stem cells.
Flow cytometry: Recommended dilution: 1-5 µg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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