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  7. Anti-Human CD369 APC MAb(Clone :15E2)

Anti-Human CD369 APC MAb(Clone :15E2)

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Fig 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD369 (15E2) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).

Anti-Human CD369 APC  MAb(Clone :15E2)
Anti-Human CD369 APC  MAb(Clone :15E2)

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Fig 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD369 (15E2) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
Fig 2: Separation of human monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD369 (15E2) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).

Product code: 30-2865

Clone name : 15E2
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

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100 tests
$443.00 

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  • Product Info
  • Antigen Details
  • Description
  • Application Note
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Amount : 100 tests
Isotype : Mouse IgG2a kappa
Purification : Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content : Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azid
Storage condition : Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Gene : CLEC7A
Gene ID : 64581
Uniprot ID : Q9BXN2
Alternative Name : C-type lectin domain containing 7A, Dectin-1, CLEC7A, BGR, CANDF4, SCARE2
Immunogen Information : Extracellular part of human CD369 with hIgG FC tag

Specificity: The mouse monoclonal antibody 15E2 recognizes an extracellular epitope LWEDGSTFSSN of human CD369 (Dectin-1), a 33 kDa transmembrane glycoprotein expressed predominantly on dendritic cells.

CD369 (dectin-1, beta-glucan receptor) is a 33 kDa type II transmembrane glycoprotein of lectin family, and serves as a part of innate immunity system by binding to beta-glucan polymers, which are typical for yeast and mycobacterial cell walls. CD369 is expressed predominantly on dendritic cells, but it can be detected also on monocytes, macrophages, mast cells, eosinophils, B cells, endothelial cells, and sometimes also on some T cell subsets.

 

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-Human CD369 APC MAb(Clone :15E2)

Product code: 30-2865
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