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    7. Anti-Human IL-6 (Sarilumab) – Fc Muted™ HRP

    Anti-Human IL-6 (Sarilumab) – Fc Muted™ HRP

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    Anti-Human IL-6 (Sarilumab) – Fc Muted™ HRP

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    Product code: 12-8092

    Clone name : Hu137
    Clonality : Monoclonal
    Application : ELISA
    Reactivity : Human

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    Size
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    100 µg
    $699.00  $559.20 

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    Shipping Info:

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    • Product Info
    • Antigen Details
    • Description
    • Application Note
    • Review   (0)
    Amount : 100 µg
    Isotype : Human IgG1k
    Content : Concentration : 0.5 mg/ml
    This HRP-conjugated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4, 1% BSA. (Warning: Use of sodium azide as a preservative will inhibit the enzyme activity of horseradish peroxidase)
    Storage condition : This horseradish peroxidase conjugated monoclonal antibody is stable when stored at 2-8°C. Do not freeze.
    Alternative Name : Interleukin-6, CDF; HGF; HSF; BSF2; BSF-2; IFNB2; IFN-beta-2

    Expression Host : HEK-293

    This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Sarilumab. Sarilumab binds to the transmembrane and soluble forms of the IL-6 receptor. This product is for research use only.
    IL-6 and its signaling pathway play a part in immune response regulation, inflammation, and hematopoiesis.2 Sarilumab is a research-grade recombinant human monoclonal IL-6 receptor antagonist. It specifically binds to both the transmembrane and soluble forms of the IL-6 receptor, thus inhibiting IL-6–mediated cis and trans-signaling in a dose-dependent manner.1 Therapeutic Sarilumab, also known by the trade name Kevzara, is currently used to treat Rheumatoid Arthritis1, however, as of March 2020, The Feinstein Institute of Northwell Health publicized a study on "a human antibody that may prevent the activity" of IL-6 for the treatment of COVID-19.3 Anti-Human IL-6 (Sarilumab) utilizes the same variable regions from the therapeutic antibody Sarilumab making it ideal for research projects.

    The suggested concentration for Alemtuzumab biosimilar antibody for staining cells in flow cytometry is <= 1.0 µg per 106 cells in a volume of 100 µl. Titration of the reagent is recommended for optimal performance for each application.ELISA

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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    Anti-Human IL-6 (Sarilumab) – Fc Muted™ HRP

    Product code: 12-8092
    *specify in mg or ml

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