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    7. Anti-Human SIGLEC8 Antibody (Clone : 7C9)

    Anti-Human SIGLEC8 Antibody (Clone : 7C9)

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    Figure 1 : Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human SIGLEC8 (7C9) purified antibody (concentration in sample 6 µg/ml; GAM APC).

    Anti-Human SIGLEC8 Antibody (Clone : 7C9)

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    Product code: 30-2496

    Clone name : 7C9
    Clonality : Monoclonal
    Application : FACS , ELISA, IP
    Reactivity : Human

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    0.1 mg
    $373.00 

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    • Product Info
    • Antigen Details
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    Format : Purified
    Amount : 0.1 mg
    Isotype : Mouse IgG1
    Purification : Purified by protein-A affinity chromatography
    Content : 1 mg/ml
    Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
    Storage condition : Store at 2-8°C. Do not freeze.
    Gene : SIGLEC8
    Gene ID : 27181
    Alternative Name : SAF2,sialic acid binding Ig like lectin 8
    Immunogen Information : Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
    SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.
    Specificity : The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.
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    Anti-Human SIGLEC8 Antibody (Clone : 7C9)

    Product code: 30-2496
    *specify in mg or ml

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