Anti-Kappa Monoclonal Antibody (Clone:IHC610)
Figure 1: Immunohistochemical analysis of Kappa (IHC610) on Ovary
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| Format : | Purified |
| Amount : | 1 ml |
| Purification : | Protein A/G Chromatography |
| Storage condition : | Store at 2°C - 8°C. |
| Gene : | IGKV1D-16 |
| Uniprot ID : | P01601 |
| Alternative Name : | Immunoglobulin kappa variable 1D-16, Ig kappa chain V-I region HK146, Ig kappa chain V-I region HK189 |
Anti-Kappa recognizes surface immunoglobulin on normal and neoplastic B-cells, and has been indicated as a potential aid in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas, where the expression of a single light chain class is restricted. The determination of light chain ratio is critical in evaluating B-cell neoplasms, as the majority of B-cell lymphomas express either kappa or lambda light chains, while a mixture of kappa and lambda is characteristic of reactive proliferations. In paraffin-embedded tissue, Anti-Kappa displays strong staining of kappa-positive plasma cells, as well as cells that have absorbed exogenous immunoglobulins.
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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