Anti-Ketamine-(Clone KET-1153)
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| Amount : | 1.0 mg |
| Isotype : | Mouse IgG2a k |
| Purification : | Purity: >90% for SDS PAGE Preparation: This monoclonal antibody is purified by ion exchange chromatography. |
| Content : | Concentration: >=1.0 mg/ml Formulation: Formulated in 0.015M potassium phosphate buffered saline (0.85%), pH 7.2 and contains 0.05% sodium azide. |
| Storage condition : | This purified antibody is stable when stored at 2-8°C.?Do not freeze. |
Specificity: Anti-Ketamine (clone KET-1153) is specific for ketamine. Ketamine - 100% Norketamine - 60%
Background: Ketamine is a nonbarbiturate dissociative anesthetic that has been approved for use in general anesthesia both alone and in combination with other medications. Ketamine's primary mechanism of action involves antagonizing N-methyl-D-aspartate (NMDA) receptors in the brain, leading to dissociation of sensory perceptions and producing analgesic and hallucinogenic effects. Recent research has shown long-lasting antidepressant activity and chronic pain relief likely due to structural brain changes induced by the drug. Ketamine has emerged as a novel and promising treatment for certain psychiatric conditions, such as treatment-resistant depression and post-traumatic stress disorder (PTSD), administered in controlled clinical settings. However, its misuse, particularly in recreational settings, raises concerns due to its dissociative effects and potential for addiction.
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