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  7. Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) Monoclonal Antibody(Clone: NX2/2198R)

Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) Monoclonal Antibody(Clone: NX2/2198R)

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Fig. 1: Formalin-fixed, paraffin-embedded human Ewing's Sarcoma stained with NKX2.2 Rabbit Recombinant Monoclonal Antibody (NX2/2198R).

Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) Monoclonal Antibody(Clone: NX2/2198R)
Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) Monoclonal Antibody(Clone: NX2/2198R)

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Fig. 1: Formalin-fixed, paraffin-embedded human Ewing's Sarcoma stained with NKX2.2 Rabbit Recombinant Monoclonal Antibody (NX2/2198R).
Fig. 2: SDS-PAGE Analysis of Purified NKX2.2 Rabbit Recombinant Monoclonal Antibody (NX2/2198R).

Product code: 36-2855

Clone name : NX2/2198R
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
  • Description
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Amount : 100 µg
Isotype : Rabbit IgG
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : NKX2-2
Gene ID : 4821
Uniprot ID : O95096
Alternative Name : Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
Immunogen Information : Recombinant human NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) Monoclonal Antibody(Clone: NX2/2198R)

Product code: 36-2855
*specify in mg or ml

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