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  7. Anti-NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME2-2)

Anti-NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME2-2)

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Fig. 1: Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with NME2 / nm23-H2 Mouse Monoclonal Antibody (CPTC-NME2-2).

Anti-NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME2-2)
Anti-NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME2-2)
Anti-NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME2-2)
Anti-NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME2-2)

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Fig. 1: Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with NME2 / nm23-H2 Mouse Monoclonal Antibody (CPTC-NME2-2).
Fig. 2: Western Blot Analysis of PC-3 cell lysate using NME2 / nm23-H2 Mouse Monoclonal Antibody (CPTC-NME2-2).
Fig. 3: SDS-PAGE Analysis Purified NME2 / nm23-H2 Mouse Monoclonal Antibody (CPTC-NME2-2). Confirmation of Purity and Integrity of Antibody.
Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using NME2 / nm23-H2 / NDPK-B Monoclonal Antibody (CPTC-NME2-2). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2864

Clone name : CPTC-NME2-2
Clonality : Monoclonal
Application : WB, IHC
Reactivity : Human

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  •  100 µg

  • $199.00 

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  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG2a, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : NME2
Gene ID : 4831
Uniprot ID : P22392
Alternative Name : C myc purine binding transcription factor PUF; C-myc purine-binding transcription factor PUF; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB;; NDP kinase B; NDPKB; nm23-H2; NM23B; NME/NM23 nucleoside diphosphate kinase 2; nme2; Nucleoside diphosphate kinase B;
Immunogen Information : Recombinant full-length human NME2 protein
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.

Western Blot (1-2µg/ml);Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME2-2)

Product code: 36-2864
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