Anti-Rotavirus (Clone ROTA-3868)
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| Amount : | 250 µg |
| Isotype : | Mouse IgG2b |
| Purification : | Purity: ≥90% Product Preparation: This monoclonal antibody is purified by protein A chromatography or sequential differential precipitations. |
| Content : | Product Concentration: ≥1.0 mg/ml Formulation: Formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. |
| Storage condition : | This purified antibody is stable when stored at 2-8°C. Do not freeze. |
Specificity
Anti-Rotavirus (Clone ROTA-3868) is specific for the intact virus of strains RRV, WA, SA11 and bovine. It is non-reactive with Influenza A and B, Adenovirus, M. pneumoniae, H. pylori, Parainfluenza Virus 1, 2, 3, and mammalian cells.
Background
Rotavirus is a highly contagious, double-stranded RNA virus that is the leading cause of severe gastroenteritis in infants and young children worldwide. It belongs to the Reoviridae family and is classified into different serotypes based on the antigenic properties of its outer protein coat. Rotavirus spreads primarily through the fecal-oral route, either by direct contact with an infected person or by consuming contaminated food or water. The virus replicates in the small intestine, leading to the destruction of the intestinal epithelial cells, which results in diarrhea, vomiting, fever, and dehydration. Rotavirus infections are particularly dangerous in developing countries with limited access to proper sanitation and healthcare, where they contribute significantly to childhood morbidity and mortality. Vaccination against rotavirus has shown to be highly effective in reducing severe rotavirus infections and associated hospitalizations.
ELISA: 1:20-1:200
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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