Anti-SARS-CoV-2 RBD antibody(DM27), Rabbit mAb
Figure 1. Competition FACS assay demonstrating Rabbit anti-RBD monoclonal antibody (clone: DM27) blockade of SARS-CoV-2 (COVID-19) S protein RBD (1µg/ml, ) binding to Expi 293 cell line transfected with human ACE2. IC50=1930ng/ml. The Y-axis represents the geometric mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.
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|Amount :||100 µg|
|Isotype :||Rabbit IgG|
|Purification :||Purified from cell culture supernatant by affinity chromatography|
|Content :||Preservative: 0.1% Procline 300
Constituents: 50% Glycerol; PBS, pH 7.4; 0.1% BSA
|Storage condition :||Store at -20°C for 12 months (Avoid repeated freezing and thawing)|
|Alternative Name :||SARS-CoV-2 RBD|
|Immunogen Information :||Recombinant SARS-CoV-2 (2019-nCoV) S protein RBD (Arg 319-Phe541) produced by using human HEK293 cells|
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as Covid19 (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. The spike protein is a type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which accounts for recognizing the cell surface receptor, ACE2. S2 contains basic elements needed for the membrane fusion. Recent publications indicate that S1-RBD domain can induce virus neutralizing-antibody and T cell response.
Recommended Dilutions FACS 1/100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.