Anti-TFE3 Monoclonal Antibody (Clone:IHC672)
|Amount :||0.5 ml|
|Isotype :||Mouse IgG1|
|Purification :||Protein A/G Chromatography|
|Content :||Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide|
|Storage condition :||Store at 2°C - 8°C. Do not freeze.|
Transcription Factor E3 (TFE3) is a transcription factor that binds to the MUE3-type E-box sequences involved in TGF-Beta signalling. Anti-TFE3 staining is the most sensitive and specific indicator of Xp11 translocation renal cell carcinomas.
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Post transnational modification:||Sumoylated; does not affect dimerization with MITF.|
|Tissue Specificity:||Ubiquitous in fetal and adult tissues.|
|BioGrid:||112888. 25 interactions.|