Biotinylated Anti-UPA antibody(DMC440); IgG1 Chimeric mAb
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| Amount : | 100 µg | 
| Isotype : | IgG1 | 
| Purification : | Purified from cell culture supernatant by affinity chromatography | 
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. | 
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. | 
| Gene : | UPA | 
| Uniprot ID : | P00749 | 
| Alternative Name : | ATF; BDPLT5; QPD; u-PA; UPA; URK | 
			This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed.		 
		
			    Flow Cyt 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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