Flagellin
Figure 1: Induction of TLR5 activity by Flagellin in TLR5/NF-kB Leeporter - HEK 293
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| Amount : | 100 µg |
| Content : | Lyophilized in PBS. |
| Storage condition : | Upon receipt, store at -20°C (Stable for at least 6 months). Reconstitute with 100 ul of sterile endotoxin free water. 1mg/ml after reconstitution. |
| Alternative Name : | FliC |
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system via Toll-like receptor 5 (TLR5) and the intracellular protein NLRC4 (NLR family CARD domain-containing protein 4).
Source: Recombinant Flagellin from Salmonella typhimurium strain 14028
Endotoxin level: <0.01 EU/µg
Specificity: TLR5 agonist
TLR5 can be stimulated in vitro by Flagellin at a concentration of 5-50ng /ml and in vivo at a starting concentration of 0.1-1µg /mouse.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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