Flagellin

Figure 1: Induction of TLR5 activity by Flagellin in TLR5/NF-kB Leeporter - HEK 293

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Product code: 15-1014

Application :	Functional Assay
Reactivity :	Mouse, Human

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Amount :	100 µg
Content :	0.5 mg/ml in PBS + 10% Glycerol
Storage condition :	Upon receipt, store at -20°C (Stable for at least 6 months). Avoid frequent freeze/thaw cycles.


Alternative Name :	FliC

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system via Toll-like receptor 5 (TLR5) and the intracellular protein NLRC4 (NLR family CARD domain-containing protein 4).

Source: Recombinant Flagellin from Salmonella typhimurium

Endotoxin level: <0.5 EU/µg

Specificity: TLR5 agonist

TLR5 can be stimulated in vitro by Flagellin at a concentration of 5-50ng /ml and in vivo at a starting concentration of 0.1-1µg /mouse.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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