G alpha 15 Stable Cell Line-FP-293-Human(Currently Unavailable)
Figure 1: Functional analysis of FP receptor.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 45% culture medium, 45% FBS, 10% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
| Alternative Name : | Human Recombinant FP Prostanoid Receptor Stable Cell Line |
Prostaglandin F (2-alpha) is known as a potent luteolytic agent. It is involved in modulating intraocular pressure and smooth muscle contraction in uterus. Its effects on cells are mediated through specific interaction with the Prostanoid receptor FP, which is a 359-amino acid protein. Having 7 putative transmembrane domains, FP resembles the characteristic of G protein coupled receptors. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thereupon induce luteolysis.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors. Culture Medium: DMEM, 10% FBS, 200 µg/ml Zeocin, 250 µg/ml G418, 100 µg/ml Hygromycin B
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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