Anti-Andes Virus (Hantavirus) (Clone: ANDV-44)
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| Amount : | 100 µg |
| Isotype : | Human IgG1 |
| Purification : | ≥95% monomer by analytical SEC |
| Content : | ≥ 5.0 mg/ml. This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Storage condition : | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≥ -70°C. Avoid Repeated Freeze Thaw Cycles. |
| Alternative Name : | Hantavirus, Orthohantavirus, ANDV |
| Immunogen Information : | This human monoclonal antibody clone ANDV-44 was generated as part of a panel using a B cell hybridoma method from an individual previously infected with ANDV. |
Reactivity Species : Andes virus-Hantavirus-Virus
Expression Host : HEK-293
Endotoxin Leve : l≤ 1.0 EU/mg as determined by the LAL method
Specificity : Clone ANDV-44 competes for binding to a distinct site on the ANDV surface glycoprotein spike, a tetrameric complex composed of Gn and Gc envelope proteins8. Furthermore, antibody ANDV-44 recognizes antigenic site C1 but does not show reactivity to soluble Gc or Gn proteins and may bind to a target site only present in the quaternary spike structure.
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