G alpha 15 Stable Cell Line-PTH1-CHO-K1-Human
Figure 1: Functional analysis of PTH1 receptor.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 45% culture medium, 45% FBS, 10% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
| Alternative Name : | Human Recombinant Parathyroid Hormone Receptor 1 Stable Cell Line |
Parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor (PTHR1) is a G protein coupled receptor which mediates the actions of both amino-terminal PTH and PTHrP fragments. The most abundant expression of PTHR1 is found in renal tubular cells and in osteoblasts, where the PTH/PTHrP receptor mediates the endocrine actions of PTH, and in prehypertrophic chondrocytes of the metaphyseal growth plate, where it mediates the autocrine/paracrine actions of PTHrP. Intact PTH (PTH 1-84) is compounded by a peptide of 84 amino acids (AA), the amino-terminal sequence, constituted by the first 34 AA (N-terminal structure), is necessary for its action.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors. Culture Medium: Ham's F12, 10% FBS, 100 µg/ml Hygromycin B, 400 µg/ml G418
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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