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    7. Monoclonal Antibody to CD10 (Clone: ABM4A52)

    Monoclonal Antibody to CD10 (Clone: ABM4A52)

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    Fig-1: Immunohistochemical analysis of CD10 in human Renal CellCarcinoma tissue using CD10 antibody (Clone: ABM4A52) at 5 µg/ml.

    Monoclonal Antibody to CD10 (Clone: ABM4A52)
    Monoclonal Antibody to CD10 (Clone: ABM4A52)
    Monoclonal Antibody to CD10 (Clone: ABM4A52)

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    Fig-1: Immunohistochemical analysis of CD10 in human Renal CellCarcinoma tissue using CD10 antibody (Clone: ABM4A52) at 5 µg/ml.
    Fig-2: Western blot analysis of CD10. Anti-CD10 antibody (Clone: ABM4A52) was tested at 0.5 µg/ml on Jurkat and Ramos lysates.
    Fig-3: Cell surface flow analysis of CD10 (10-7560) in PBMC using 0.5 µg/10^6 cells of CD10 antibody (Clone: ABM4A52). Green represents isotype control (ABEOMICS); red represents anti-CD10 antibody. Goat anti-Mouse PE conjugate was used as secondary.

    Product code: 10-7560

    Clone name : ABM4A52
    Clonality : Monoclonal
    Application : IHC, FACS, WB
    Reactivity : Human

    Shipping Info:

    Order now and get it on Tuesday July 05, 2022

    Same day delivery FREE on San Diego area orders placed by 1.00 PM

    Local delivery areas

    Same-day delivery in San Diego available for the following zip codes:

    92121, 92122, 92037, 92117, 92109, 92110, 92101, 92010, 92011, 92009, 92008
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    Price

    Available Pack Size(s)

    •   25 µg

    •  100 µg

    • $100.00 

    • $230.00 

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    Shipping Info:

    Order now and get it on Tuesday July 05, 2022

    Same day delivery FREE on San Diego area orders placed by 1.00 PM

    Download TDS MSDS

    • Product Info
    • Antigen Details
    • Description
    • Application Note
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    • Review   (0)
    Format : Purified
    Amount : 100 µg
    Isotype : Mouse IgG2b Kappa
    Purification : Protein G Chromatography
    Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
    Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
    Gene : MME
    Gene ID : 4311
    Uniprot ID : P08473
    Alternative Name : MME, EPN
    Immunogen Information : A partial length recombinant CD10 protein (amino acids 282-496) was used as the immunogen for this antibody.

    CD10, also known as membrane metalloendopeptidase, neutral endopeptidase, neprilysin and common acute lymphoblastic leukaemia antigen (CALLA), is a zinc-dependent metalloendoprotease that cleaves signaling peptides. It is widely expressed in various normal tissues and in epithelial, stromal or both components of various malignancies. CD10 is a marker for intestinal epithelial brush border. It is also present in normal bile ducts and gallbladder epithelia but is absent in cholangiocarcinomas. It is con-sidered as the prototype of this family of membrane-bound, zinc-dependent endopeptidases, which regulate the physiological action of various peptides by lowering their extracellular concentration available for receptor binding. CD10 is also known to be an amyloid b-peptide (Ab) degrading enzyme. Polymorphisms in the CD10 gene increase the risk for Alzheimers disease. Outside the nervous system, it is present on the surface of neutrophils and regulates their activation by degradation of inflammatory peptides.

    Western blot analysis: 0.5-1 µg/ml; Immunohistochemical analysis: 5-10 µg/ml, FACS: 0.5-2 µg/10^6 cells

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Cell membrane
    Post transnational modification: Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity.
    BioGrid: 110455. 102 interactions.
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    Monoclonal Antibody to CD10 (Clone: ABM4A52)

    Product code: 10-7560
    *specify in mg or ml

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