Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Other Kits
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Immunology
  6. /
  7. Monoclonal Antibody to human CD36

Monoclonal Antibody to human CD36

Share:

Figure-1: Flow cytometry: detection of CD36 in THP-1 cells. Red, black and blue line represent the isotype control, cells only and 10-3544 with a Concentration of 10 µg/ml, respectively.

Monoclonal Antibody to human CD36

Roll over image to zoom in

   

Product code: 10-3544

Clone name : FA6-152
Clonality : Monoclonal
Application : FACS, IF
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   100 µg

  •  500 µg

  • $754.00 

  • $1,745.00 

Add to Wish List

Bulk Order

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • Review   (0)
Amount : 500 µg
Isotype : Mouse IgG1
Content : 0.5 mg 0.2 µm filtered protein G purified antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
Storage condition : Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
Gene : CD36
Gene ID : 948
Uniprot ID : P16671
Alternative Name : GP3B, GP4, Fatty acid translocase, Glycoprotein IIIb, Leukocyte differentiation antigen CD36, PAS IV, PAS-4,
Immunogen Information : 20-Weeks-old fetal erythrocytes

Monoclonal antibody FA6-152 recognizes human CD36 (88-kDa), a cell surface class B scavenger receptor, also known as thrombospondin receptor CD36 is a heavily N-glycosylated transmembrane protein of ~88 kDa with two short intracellular domains and a large extracellular domain. The protein is sensitive for neuroaminidase, resulting in a shift from 88 to 85 kDa. CD36 is expressed on platelets, mature monocytes and macrophages, microvascular endothelial cells, mammary endothelial cells, during stages of erythroid cell development and on some macrophage derived dendritic cells. The antibody recognizes adult and fetal monocytes, platelets and reticulocytes, but doesn’t stain lymphocytes and granulocytes. Reactivity has also been found in small intestine, kidney, liver and thyroid. CD36 expression is primarily controlled by the transcription heterodimer PPARg-RXR (peroxisome proliferator-activated receptor-g-retinoid-X-receptor). CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adaptor molecules. It is a receptor and transporter of oxidized lipids and long chain fatty acids. CD36 has been implicated in many biological processes including angiogenesis, phagocytosis, inflammation, and lipid and glucose metabolism. Several in vivo models support the role of the thrombospondin / CD36 system in angiogenesis and tumor growth. An important role for CD36 has been found in Malaria as major receptor for P. falciparum-infected red blood cells. CD36 is associated with Src-family kinases and with the integrins alpha3 beta1 and alpha6 beta1. Recently, CD36 has been identified as a protein that is required for toll like receptor (TLR2) recognition of di-acylated bacterial lipopeptides and lipoteichoic acid4. Furthermore, CD36 has been shown to function as phagocytic receptor for apoptotic cells. Many different ligands have been reported to interact with CD36, suggesting that CD36 could recognize a structure-based domain rather than specific contact residues. Monoclonal antibody FA6-152 blocks the biological activity of CD36 by blocking collagen/thrombospondin binding. The antibody agglutinates fetal but not adult erythrocytes.

IHC-F: Tissue embedded in tissue-tek (for instance aortic tissue) followed by freezing in liquid nitrogen; 7-8 µm sections; air-dried; aceton-fixed; 10 % NGS as block . FACS Analysis: Antibody FA6-152 stains the extracellular domain of CD36. Unfixed cells;2 µg per 100.000 cells. Positive on granulocytes . FUnctional studies: Platelet aggregation and secretion was induced by; 1 µg/ml antibody . Immuno Assay: 10 µg/ml antibody as coat diluted in Tris-buffered saline ; 100 µml/well; o/n at RT. Immuno Fluoroscence: unfixed cells were incubated for 30 minutes at 4 °C followed by a secondary FITC polyclonal antibody; one-minute methanol fixation before analysis . Immuno Precipitation: 88 kDa sialoglycoprotein in platelets; 85 and 88 kDa in HEL cells. 10 µg antibody/200 µg protein. Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

SARS-CoV-2 Spike Protein S1 (RBD) Fc Tag

SARS-CoV-2 Spike Protein S1 (R...

details-SARS-CoV-2 Spike Protein S1 (RBD) Fc Tag
Anti-TNFRSF10B Antibody (tigatuzumab biosimilar) (GEN-1029)

Anti-TNFRSF10B Antibody (tigat...

details-Anti-TNFRSF10B Antibody (tigatuzumab biosimilar) (GEN-1029)
Recombinant Human Transcription Factor B1, Mitochondrial

Recombinant Human Transcriptio...

details-Recombinant Human Transcription Factor B1, Mitochondrial
TNF-beta Leeporter™ Luciferase Reporter-HEK293 Cell Line

TNF-beta Leeporter™ Lucifera...

details-TNF-beta Leeporter™ Luciferase Reporter-HEK293 Cell Line
Recombinant human CXCL1 protein with C-terminal human Fc tag

Recombinant human CXCL1 protei...

details-Recombinant human CXCL1 protein with C-terminal human Fc tag
Anti-SOX-11 Monoclonal Antibody (Clone:IHC011)

Anti-SOX-11 Monoclonal Antibod...

details-Anti-SOX-11 Monoclonal Antibody (Clone:IHC011)
Recombinant human TIE2 protein with C-terminal human Fc tag

Recombinant human TIE2 protein...

details-Recombinant human TIE2 protein with C-terminal human Fc tag
Anti-CD57 Monoclonal Antibody (Clone:IHC539)

Anti-CD57 Monoclonal Antibody ...

details-Anti-CD57 Monoclonal Antibody (Clone:IHC539)
Anti-Basic Cytokeratins Monoclonal Antibody (Clone:AE3)

Anti-Basic Cytokeratins Monocl...

details-Anti-Basic Cytokeratins Monoclonal Antibody (Clone:AE3)
Anti-p57 kip2 Monoclonal Antibody (Clone:IHC057)

Anti-p57 kip2 Monoclonal Antib...

details-Anti-p57 kip2 Monoclonal Antibody (Clone:IHC057)
Monoclonal Antibody to RIG-I (Clone: ABM4H29)

Monoclonal Antibody to RIG-I (...

details-Monoclonal Antibody to RIG-I (Clone: ABM4H29)
Coronavirus (COVID-19) Nucleocapsid Antibody

Coronavirus (COVID-19) Nucleoc...

details-Coronavirus (COVID-19) Nucleocapsid Antibody
VEGF Mouse, Yeast

VEGF Mouse, Yeast

details-VEGF Mouse, Yeast
CD80 Stable Cell Line

CD80 Stable Cell Line

details-CD80 Stable Cell Line

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin

Related Products

Mouse Anti-Chicken ChT1-PE

Mouse Anti-Chicken ChT1-PE

Mouse Anti-Human CD3-APC/CY7

Mouse Anti-Human CD3-APC/CY7

Rat Anti-Mouse CD11b-CY5

Rat Anti-Mouse CD11b-CY5

New Products

Recombinant TLR9 Protein with human Fc Tag

Recombinant TLR9 Protein with human Fc Tag

Anti-IL-17A (Taltz) (Ixekizumab biosimilar) mAb

Anti-IL-17A (Taltz) (Ixekizumab biosimilar) mAb

Anti-IL-1beta (Canakinumab biosimilar) mAb

Anti-IL-1beta (Canakinumab biosimilar) mAb

close

Please Login to write a Review !!


close

Monoclonal Antibody to human CD36

Product code: 10-3544
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart