Mouse Anti-Human CD16-R-PE/CY5 (Clone: GRM1)
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| Amount : | 100 Tests |
| Isotype : | Mouse IgG2a |
| Content : | 1.0 ml, Supplied in PBS/Sodium azide and a stabilizing agent |
| Storage condition : | Store at 2-8°C |
CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.
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For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Secreted |
| Post transnational modification: | The soluble form is produced by a proteolytic cleavage. |
| Tissue Specificity: | Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. |
| BioGrid: | 108508. 11 interactions. |
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