Anti-Cytokeratin 8 Monoclonal Antibody (Clone:C-43)
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml
positive tissue: prostate.
Flow cytometry: Recommended dilution: 1-5 μg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasm, Nucleus, Nucleus matrix |
| Post transnational modification: | O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner. |
| Tissue Specificity: | Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. |
| BioGrid: | 110054. 69 interactions. |
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