Mouse Monoclonal Antibody to CEA(Clone :BS33)
Figure-1: Human colon have been stained using CEA antibody (Clone: BS33). Carcinoembryonic antigen (CEA) is expressed in the apical border of the columnar cells of colon. Specific staining. No staining of leucocytes. No staining in liverX100.
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CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).The carcinoembryonic antigen (CEA) is a member of a large family of glycoproteins and a useful tumor marker for adenocarcinoma. Tissue specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
| Content : | TRIS with 0.03% sodium azide, pH7.2 |
| Storage condition : | Store at 4°C |
Immunohistochemical Analysis :-1:250
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Apical cell membrane, Cell surface |
| Post transnational modification: | Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. |
| Tissue Specificity: | Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. |
| BioGrid: | 107478. 6 interactions. |
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