Mouse Monoclonal Antibody to CEA(Clone :BS33)
CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+).The carcinoembryonic antigen (CEA) is a member of a large family of glycoproteins and a useful tumor marker for adenocarcinoma. Tissue specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
|Content :||TRIS with 0.03% sodium azide, pH7.2|
|Storage condition :||Store at 4°C|
Immunohistochemical Analysis :-1:250
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Subcellular location:||Cell membrane, Apical cell membrane, Cell surface|
|Post transnational modification:||Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.|
|Tissue Specificity:||Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.|
|BioGrid:||107478. 6 interactions.|