Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Immune-Check Point
        • Kits and Reagents
          • Luciferase reporter assay kits
          • Inhibitor Screening Kit
          • ELISA Kits
          • Molecular Biology Kits
          • Apoptosis Detection kits
          • Flowcytometry staining kits
          • Cell dissociation solutions
          • Western Blot membranes (Quick blots/ Q Blots)
        • Tissue Microarray
        • recmAb™
          • Recombinant Biosimilar Antibodies
          • Recombinant Rabbit Antibodies
          • Recombinant Mouse Antibodies
    • Pathways
        • All-Pathways

          View all pathways

        • interactive-pathways

          View all interactive pathways

    • Custom Service
      • Drug Discovery Screening Services
      • Stable Cell Line Development
      • Protein Production
      • Custom Antibody Development
    • Quick order
      • + Add More..

    • Support
    • Contact us
    • Distributors
    1. Catalog
    2. /
    3. Antibodies
    4. /
    5. Immunology
    6. /
    7. Mouse Monoclonal Antibody to IL-8 (Clone : 1A7C8)(Discontinued)

    Mouse Monoclonal Antibody to IL-8 (Clone : 1A7C8)(Discontinued)

    Share:

    Figure-1 : Western blot analysis of Human IL-8 Antibody (Clone: 1A7C8) at 1 µg/ml on human recombinant IL-8 fusion protein, IRDye 800 Conjugated Goat Anti-Mouse IgG was used as secondary antibody.

    Mouse Monoclonal Antibody to IL-8 (Clone : 1A7C8)(Discontinued)
    Mouse Monoclonal Antibody to IL-8 (Clone : 1A7C8)(Discontinued)
    Mouse Monoclonal Antibody to IL-8 (Clone : 1A7C8)(Discontinued)

    Roll over image to zoom in

       
    Figure-1 : Western blot analysis of Human IL-8 Antibody (Clone: 1A7C8) at 1 µg/ml on human recombinant IL-8 fusion protein, IRDye 800 Conjugated Goat Anti-Mouse IgG was used as secondary antibody.
    Figure-2 : Sandwich ELISA analysis of Human IL-8 Antibody (Clone: 1A7C8) on matched antibody pairs 1) ELISA plate was coated with Human IL-8 Antibody(1A7C8). 2) Human recombinant IL-8 protein at appropriate dilution was added into appropriate reaction wells. 3) After a period of incubation, HRP conjugated Human IL-8 Antibody (Clone. 2D11C10 ,  3D4C3 and  4H7C7) was added followed by proper period of incubation.
    Figure-3 : ELISA analysis of Cross reactivity using Human IL-8 Antibody (Clone: 1A7C8).

    Product code: 45-1051

    Clone name : 1A7C8
    Clonality : Monoclonal
    Application : ELISA
    Reactivity : Human

    Shipping Info:

    For estimated delivery dates, please contact us at support@abeomics.com

    Download TDS MSDS
    Write a review for this product on BioCompare
    Get $20 gift card from Amazon

    Shipping Info:

    For estimated delivery dates, please contact us at support@abeomics.com

    Download TDS MSDS

    • Product Info
    • Antigen Details
    • Description
    • Application Note
    • More
    • Review   (0)
    Format : Purified
    Amount : 40 µg
    Isotype : Mouse IgG1, κ
    Purification : Protein A chromatography
    Content : 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
    Storage condition : The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
    Gene : CXCL8
    Gene ID : 3576
    Uniprot ID : P10145
    Alternative Name : C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, Emoctakin, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, T-cell chemotactic factor
    Immunogen Information : Amino acids sequence: MTSKLAVALL AAFLISAALC EGAVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KELKRAENS

    IL-8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins is proinflammatory and primarily mediates the activation and migration of neutrophils from peripheral blood into tissue. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL-8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology. Human IL-8 Antibody (1A7C8), mAb, Mouse was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide. The animals cells produce the protein, which stimulates the animals immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper, and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity, and native protein recognization.

    ELISA Capture: 0.5-10 µg/ml
    ELISA Detection: 0.05-0.2 µg/ml
    Western blot: 1-2 µg/ml
    Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Secreted
    Post transnational modification: Citrullination at Arg-27 prevents proteolysis, and dampens tissue inflammation, it also enhances leukocytosis, possibly through impaired chemokine clearance from the blood circulation.
    BioGrid: 109790. 12 interactions.
    There are currently no product reviews
    Write a review on this product!

    Customers who purchased this product also purchased

    Mouse Monoclonal Antibody to Phosphotyrosine (Clone : 5E10E1)(Discontinued)

    Mouse Monoclonal Antibody to P...

    details-Mouse Monoclonal Antibody to Phosphotyrosine (Clone : 5E10E1)(Discontinued)
    Biotinylated Recombinant Human Polymeric Immunoglobulin Receptor/PIgR (C-His)

    Biotinylated Recombinant Human...

    details-Biotinylated Recombinant Human Polymeric Immunoglobulin Receptor/PIgR (C-His)
    Human aFGF / FGF1 Recombinant Protein(Discontinued)

    Human aFGF / FGF1 Recombinant ...

    details-Human aFGF / FGF1 Recombinant Protein(Discontinued)
    Anti-MEK1/2 Antibody

    Anti-MEK1/2 Antibody

    details-Anti-MEK1/2 Antibody
    Monoclonal Antibody to Human TLR6 (Clone :  TLR6.127)

    Monoclonal Antibody to Human T...

    details-Monoclonal Antibody to Human TLR6 (Clone :  TLR6.127)
    CHI3L2 Recombinant Protein

    CHI3L2 Recombinant Protein

    details-CHI3L2 Recombinant Protein
    Polyclonal Antibody to NALP3

    Polyclonal Antibody to NALP3

    details-Polyclonal Antibody to NALP3
    Anti-Human CD369 Antibody (Clone : 15E2)

    Anti-Human CD369 Antibody (Clo...

    details-Anti-Human CD369 Antibody (Clone : 15E2)
    ACOT8 Recombinant Protein

    ACOT8 Recombinant Protein

    details-ACOT8 Recombinant Protein
    Anti-Human CD15 FITC (Clone : MMA)

    Anti-Human CD15 FITC (Clone : ...

    details-Anti-Human CD15 FITC (Clone : MMA)
    Anti-Daxx / DAP6 Monoclonal Antibody (Clone:DAXX-03)

    Anti-Daxx / DAP6 Monoclonal An...

    details-Anti-Daxx / DAP6 Monoclonal Antibody (Clone:DAXX-03)
    Anti-MSLN antibody(DM73), Rabbit mAb

    Anti-MSLN antibody(DM73), Rabb...

    details-Anti-MSLN antibody(DM73), Rabbit mAb
    Anti-2B4 antibody(DM69), Rabbit mAb

    Anti-2B4 antibody(DM69), Rabbi...

    details-Anti-2B4 antibody(DM69), Rabbit mAb
    HbA1c Native Protein

    HbA1c Native Protein

    details-HbA1c Native Protein

    Most viewed Products

    Recombinant Human Thioredoxin-Like 4A

    Recombinant Human Thioredoxin-Like ...

    details-Recombinant Human Thioredoxin-Like 4A
    Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

    Monoclonal Antibody to Human IL-1be...

    details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
    NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

    NF-kB Leeporter™ Luciferase Repor...

    details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
    Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

    Monoclonal antibody to Human PD-L1 ...

    details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
    Polyclonal Antibody to Beta actin

    Polyclonal Antibody to Beta actin

    details-Polyclonal Antibody to Beta actin
    Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

    Monoclonal Antibody to Caspase-3 (P...

    details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
    Monoclonal Antibody to GAPDH (Clone: ABM22C5)

    Monoclonal Antibody to GAPDH (Clone...

    details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
    Monoclonal antibody to B7-H4 (Clone: ABM53A6)

    Monoclonal antibody to B7-H4 (Clone...

    details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
    Polyclonal Antibody to Beta Tubulin

    Polyclonal Antibody to Beta Tubulin

    details-Polyclonal Antibody to Beta Tubulin
    Peroxidase conjugated Goat anti Mouse IgG (H+L)

    Peroxidase conjugated Goat anti Mou...

    details-Peroxidase conjugated Goat anti Mouse IgG (H+L)

    Related Products

    Mouse Anti-Human ZAP-70-HRP Conjugated

    Mouse Anti-Human ZAP-70-HRP Conjugated

    Anti-HLA-E Antibody (Clone : 3D12)

    Anti-HLA-E Antibody (Clone : 3D12)

    Anti-CD49b / Integrin alpha 2 Monoclonal Antibody (Clone:AK7)-PE Conjugated

    Anti-CD49b / Integrin alpha 2 Monoclonal Antibody (Clone:AK7)-PE Conjugated

    close

    Please Login to write a Review !!


    close

    Mouse Monoclonal Antibody to IL-8 (Clone : 1A7C8)(Discontinued)

    Product code: 45-1051
    *specify in mg or ml

    Abeomics Logo

    Antibodies & Engineered Cell Lines™

    Tel : 858-263-4982

    Fax : 858-247-7052

    Email : support@abeomics.com

    Connect with Us

    • Facebook
    • Twitter
    • Linkedin
    • YouTube

    Products

    • Antibodies
    • Cell Lines
    • Ligands and Inhibitors
    • Recombinant Proteins
    • Immune-Check Point
    • Kits and Reagents
    • Tissue Microarray
    • recmAb™

    Services

    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development

    Quick order

    + Add More..

    Newsletter

    Posters and Flyers

    © 2022 Abeomics. All rights reserved.
    • Blog
    • Sitemap
    • Terms
    • Privacy Policy
    • Legal
    • Email unsubscribe

    Item added to cart successfully

    No cart item available
    Continue shopping View Cart