Mouse Monoclonal Antibody to UCHL1 (C-term)(Clone: 696CT2.1.4)(Discontinued)

Product code: 10-6599

Clone name : 696CT2.1.4
Clonality : Monoclonal
Application : WB, IHC-P
Reactivity : Human, Rat

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For estimated delivery dates, please contact us at [email protected]

Format : Purified
Amount : 400 µl
Isotype : Mouse IgG1
Purification : Protein G Chromatography
Content : Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Storage condition : Maintain refrigerated at 2-8°C for up to 2 weeks. For long term store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene : UCHL1
Gene ID : 7345
Uniprot ID : P09936
Alternative Name : Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, 6---, Neuron cytoplasmic protein 95, PGP 95, PGP95, Ubiquitin thioesterase L1, UCHL1
Immunogen Information : Synthetic Peptide
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

IHC-P~1:25|| WB~1:1000

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Endoplasmic reticulum membrane
Post transnational modification: O-glycosylated.
Tissue Specificity: Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
BioGrid: 113192. 58 interactions.
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