NK2 Stable Cell Line-CHO-K1-Human
Figure 1: Functional analysis of NK2 receptor.
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| Alternative Name : | Human Recombinant NK2 Tachykinin Receptor Stable Cell Line |
| Amount : | 2 vials |
Tachykinins are peptides sharing a common C-terminal amino acid sequence: Phe-X-Gly-Leu-Met-NH2. This neuropeptide family is composed of substance P, neurokinin A, and neurokinin B, which are widely distributed in mammalian central and peripheral nervous systems. These three molecules serve as both neurotransmitters and neuromodulators. Their actions are mediated by binding with three distinct receptors, namely NK1, NK2, and NK3. In particular, NK2 is expressed in gastrointestinal tract. Activation of NK2 is chiefly responsible for the regulation of intestinal motor functions (both excitatory and inhibitory), secretions, inflammation, and visceral sensitivity. Antagonists of NK2 may be useful in the treatment of irritable bowel syndrome.
| Content : | Each Vial contains cells in 45% culture medium, 45% FBS, and 10% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors. Culture Medium: Ham's F12, 10% FBS, 400 µg/ml G418
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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