PD-1 Stable Cell Line-CHO-K1-Cynomolgus(Currently Unavailable)
Figure 1: Flow cytometry analysis of cyno PD-1 expression in CHO-K1/cyno PD-1 cells.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 95% complete growth medium+ 5% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
| Alternative Name : | PDCD1, CD279, PD1, SLEB2, hPD-1, hPD-l, hSLE1, Programmed cell death 1 |
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein that in humans is encoded by the PDCD1 gene. PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells).
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting. Culture Medium: F12K, 10% FBS, 8 µg/ml Puromycin
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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