PE-conjugated Anti-4-1BB Ligand antibody(DM68); Rabbit mAb
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| Amount : | 100 Test |
| Isotype : | Rabbit IgG |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Liquid PBS with 0.05% Proclin300, 1% BSA |
| Storage condition : | Store?at?2 ?C-8 ?C?for?6?months |
| Gene : | 4-1BB Ligand |
| Uniprot ID : | P41273 |
| Alternative Name : | 4-1BB Ligand;TNFSF9;CD137L |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9:4-1BB; which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9:4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene; TNFSF9:4-1BBL; has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines; and is thought to be involved in T cell-tumor cell interaction.
Flow Cyt 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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