Rabbit Polyclonal Antibody to Histone 2B(Discontinued)

Product code: 45-1035

Clonality : Polyclonal
Application : ELISA
Reactivity : Human

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Format : Purified
Amount : 40 µg
Isotype : Rabbit IgG
Purification : Immunoaffinity chromatography
Content : 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Storage condition : The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Gene : HIST1H2BM
Gene ID : 8342
Uniprot ID : Q99879
Alternative Name : Histone H2B type 1-M, Histone H2B.e
Immunogen Information : Synthetic peptide derived from the carboxyl terminal of human histone 2B .

Histone 2B is the core component of nucleosome. It is involved in nucleosome wrapping and the compaction of DNA into chromatin, limiting DNA accessibility. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated via a complex system of nucleosome remodelling and post-translational modification of histones, also called histone code. Rabbit Anti-Histone 2B Polyclonal Antibody is developed in rabbit hosts using a KLH-coupled synthetic peptide corresponding to carboxyl terminal residues of human histone 2B protein (Swiss Prot: Q99879).

ELISA: 0.05-0.2 µg/ml
Western blot: 1-2 µg/ml
Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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