Recombinant Human Activin Receptor-Like Kinase 1/ALK-1(C-Fc)
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| Amount : | 50 µg |
| Content : | Lyophilized from a 0.2 µm filtered solution of PBS,pH7.4. |
| AA sequence : | Recombinant Human Activin Receptor-Like Kinase 1 is produced by our Mammalian expression system and the target gene encoding Asp22-Gln118 is expressed with a Fc tag at the C-terminus. |
| Alternative Name : | Serine/Threonine-Protein Kinase Receptor R3; SKR3; Activin Receptor-Like Kinase 1; ALK-1; TGF-B Superfamily Receptor Type I; TSR-I; ACVRL1; ACVRLK1; ALK1 |
Source : Human Cells;
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-Betasuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-Betasuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair
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