Recombinant Human Ephrin A Receptor 4/EphA4 (C-Fc)
|Amount :||50 µg|
|Content :||Lyophilized from a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,pH8.0.|
|AA sequence :||Recombinant Human Ephrin A receptor 4 is produced by our Mammalian expression system and the target gene encoding Val20-Thr547 is expressed with a Fc tag at the C-terminus.|
|Alternative Name :||Ephrin type-A receptor 4,HEK8, SEK, TYRO1,EPHA4,Tyrosine-protein kinase receptor SEK,Tyrosine-protein kinase TYRO1,EK8,hEK8,EPH-like kinase 8|
Ephrin type-A receptor 4(EPHA4) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHA4 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.